Abstract: To study the influence of flyer parameters on shock and detonation, Lee-Tarver ignition and growth model was adopted to simulate the process that flyers shock and detonate HNS-IV explosive, where the flyer was made by different materials,thickness and diameter. The influence of different flyer parameters on detonation threshold was analyzed. The results show that the shock initiation kinetic energy of polyimide was lower than those of glass and ceramic, which makes it an ideal material for lower-energy of shock initiation devices. The detonation threshold velocity decreases as the flyer thickness increases in a range from 25 to 145 μm, but when the flyer thickness exceeds 145 μm, the threshold velocity has no obvious change. In a diameter range from 1.02 to 1.57 mm, the threshold velocity gradually decreases with the increase of flyer diameter, the threshold velocity tends to be a constant value when the flyer diameter exceeds 1.57 mm.