Abstract: In order to solve the problem of route-choice of multi-destination trip, radiation field method is put forward, by integrating evaluation index, and radiation field of the different importance degree target are respectively studied. Then, combined with the discrete dynamic Bayesian network, the route choice decision model of multi-destination travel for driver is established. The model is validated by simulation through concrete examples, results show that, combined radiation field method and discrete dynamic Bayesian networks method have good applicability for the route-choice decision of multi-destination travel.