Abstract: Key pre-distribution and management scheme of wireless sensor network based on Hash constructed by look-up table is proposed in this paper. The scheme dynamically generates the public keys for nodes communication through the look-up table encryption algorithm, which can encrypt and hash the text at the same time. To improve the connectivity and livability of the network and also to save the memory, the clustered sensor network style is introduced. Theoretical analysis and computer simulation indicate that the presented scheme can improve the performance of security, connectivity, anti-captured ability and can effectively utilize the memory as well.