Abstract: Computer virus and biological virus are similar in their essence. From the viewpoint of control, the paper discusses the similarity of computer immunology and biological immunology. The validity and practicability of the multi agent technology when applied to biologically inspired computer immune systems are studied. Examples of the system are demonstrated, along with the analysis of advantages and disadvantages for each case. It is predicted that the new technology must have extensive application prospects. Directions in further study are pointed out.