Abstract: To speed up compute of motion estimation, which is the significant component in electronic image stabilization system, an efficient method making use of compound language programming is presented. According to the MMX instructions provided in Pentium microprocessor of Intel Corporation, the inline MMX assembler is used in Visual C++ program. Due to high efficiency and high speed of MMX assemble language, this method can greatly accelerate the speed of motion estimation, and reduces the consumption of compute. This method effectively meets the demand of motion estimation in electronic image stabilizations system.