Abstract: It is well known that the control of wastrwater is very important to health . In this paper a method is presented to separate organic pollutants in wastewater and to analyze them by 1R , MS and HPLC . The organic pollutants were absorbed by GDX-104 resin from wastewaler and eluted with dichlorome -thane/ acetonitrile (80/20). The eluates were concentrated about one hundred times . Then , the samples were separated by TLC . HMX , RDX , SEX and 1 , 5 -dinitroxyl - 2 , 4-dinitro - 2 , 4 - nitrogen heterocyclic pentance were identified from wastewater . Reversed phase high-performance liquid chromatography was applied for the quantitative determination of the compounds in wastewater .