Abstract: Dynamic behavior of aluminum alloy under high-speed micro-particle impact is of great importance for the structural safety design under extreme environments. The dynamic response of 2024 aluminum alloy was investigated through laser induced micro-particle impact tests and simulations. First, laser-induced particle impact tests were conducted to obtain kinetic energy dissipation of the micro-particles and the local deformation behavior of the aluminum alloy plate at room temperature, and the finite element model was validated by the experimental results. Then, phase field modeling was employed to obtain the microstructure characteristics of the solid-liquid coexisting aluminum alloy at a temperature near the melting point, from which the fluid-solid coupling simulation model was established. With this method, the characteristics of impact energy dissipation, stress distribution, deformation and failure behavior of the solid-liquid coexisting aluminum alloy were analyzed. The simulation results show that the fluid-solid interaction under dynamic loadings plays an important role in the mechanical response of the solid-liquid coexisting aluminum alloy. The energy absorption efficiency decreases at such a high temperature, and the dynamic stress transmission varies significantly due to the interaction between solid dendritic crystals.